Rocco D'Antuono
Microscopist & image analyst
Confocal, multiphoton and intravital
Wide-field, TIRF
FLIM, FCS
Imaging platforms: Leica, Zeiss, Olympus, Nikon, LaVision BioTech, BD
Programming: ImageJ macro, μManager beanshell, Java, python, R, html
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Rocco D'AntuonoMicroscopist & image analystConfocal, multiphoton and intravital Wide-field, TIRF FLIM, FCS Imaging platforms: Leica, Zeiss, Olympus, Nikon, LaVision BioTech, BD Programming: ImageJ macro, μManager beanshell, Java, python, R, html |
| Contacts: |
| rocco.dantuono@crick.ac.uk |
| https://www.linkedin.com/in/rocco-dantuono/ |
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Bio Biophysics education at Laboratory for Advanced BioSpectroscopy (UniMiB)
Microscope trainer, image acquisition and image analysis teaching:
FACS & sorting operator (2014-2017), Mass Spec beginner (2017). EUBIAS (2013) and NEUBIAS son (2017-2019) and trainer (TS12, 2019). NEUBIAS Academy organization committee (2020-2021) Data Analysis in IMaging (DAIM) RMS Section committee (2021-2024) Global BioImage Analysts' Society (GloBIAS) Founder and Steering Committee member (2023-2024) Scientific society memberships: Royal Microscopical Society, European Microscopy Society, Institute of Physics, IEEE
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Current role: Principal Microscopist and Image Analyst Crick Advanced Light Microscopy, The Francis Crick Institute, London (UK) |
from CALM website
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Previous role: 2018-2023 Senior Microscopist Crick Advanced Light Microscopy, The Francis Crick Institute, London (UK) |
from CALM website
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Previous role: 2014-2017 Imaging facility Institute for Research in Biomedicine, Bellinzona (CH) |
Gut crypts 3D reconstruction
Nat. Comms. 2019 |
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Previous role: 2011-2014 Microscopy facility IFOM, FIRC Institute for Molecular Medicine, Milan (IT) |
Focal adhesions - TIRF
Dev. Cell. 2014 |
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Education: MSc Physics, Prof. Giuseppe Chirico, Laboratory for Advanced BioSpectroscopy, University of Milano-Bicocca, Milan (IT) BSc Physics, University of Milano-Bicocca, Milan (IT) |
University is also fun
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Publications: |
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Endothelial AHR activity prevents lung barrier disruption in viral infection - Nature 621, 813–820 (2023)
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Photoablation at single cell resolution and its application in the Drosophila epidermis and peripheral nervous system - Front. Physiol., 04 January 2023
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Fluorescence fluctuation-based super-resolution microscopy: Basic concepts for an easy start - J. Microsc.2022;288:218–241
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Towards super-resolved terahertz microscopy for cellular imaging - J. Microsc.2022;288:207–217
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Extending resolution within a single imaging frame - Nat Commun 13, 7452 (2022)
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GIANI – open-source software for automated analysis of 3D microscopy images - J Cell Sci (2022) 135 (10): jcs259511
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ZELDA: A 3D Image Segmentation and Parent-Child Relation Plugin for Microscopy Image Analysis in napari - Front. Comput. Sci., 2022
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Multilayered regulation of autophagy by the Atg1 kinase orchestrates spatial and temporal control of autophagosome formation - Molecular Cell 81, 5066–5081
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Highlights from the 2016-2020 NEUBIAS training schools for Bioimage Analysts: a success story and key asset for analysts and life scientists [version 1; peer review: 2 approved] - F1000Research 2021, 10:334
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Neutrophil subtypes shape HIV-specific CD8 T-cell responses after vaccinia virus infection - NPJ Vaccines, 2021 Apr 12;6(1):52
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CDCP1 overexpression drives prostate cancer progression and can be targeted in vivo - J Clin Invest. 2020;130(5):2435-2450
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Protection against influenza infection requires early recognition by inflammatory dendritic cells through C-type lectin receptor SIGN-R1 - Nature Microbiology volume 4, pages1930-1940(2019)
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ATP released by intestinal bacteria limits the generation of protective IgA against enteropathogens - Nat.
Comm. 10, (2019) |
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Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor
Inhibition in Advanced Prostate Cancer - Cell Reports, Vol.22, Issue 8, Pages 2156-2168.e5 (2019)
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Epigenetic Control of Mitochondrial Fission Enables Self-Renewal of Stem-like Tumor Cells in Human
Prostate Cancer - Cell Metabolism, Vol. 30, Issue 2, Pages 303-318.e6 (2019)
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ER-to-lysosome-associated degradation of proteasome-resistant ATZ polymers occurs via
receptor-mediated vesicular transport - The EMBO Journal, e99259 (2018)
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Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate
cancer - Nature Genetics, Vol. 50, pages219-228 (2018)
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Mitochondrial dysfunction induced by a SH2 domain-targeting STAT3 inhibitor leads to metabolic synthetic
lethality in cancer cells - Proc Natl Acad Sci U S A (2017)
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Macrophage Death following Influenza Vaccination Initiates the Inflammatory Response that Promotes
Dendritic Cell Function in the Draining Lymph Node - Cell Rep (2017) vol. 18 pp2427-2440
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Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven
cellular senescence - Nat Commun (2016) vol. 7 pp13719
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Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery - Nat Cell Biol
(2016) vol. 18 pp1173-1184
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Reduced DNA methylation and hydroxymethylation in patients with systemic mastocytosis - Eur J
Haematol (2015) vol. 95 pp566-75
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DEPDC1B Coordinates De-adhesion Events and Cell-Cycle Progression at Mitosis - Dev Cell (2014) vol.
31 pp420-433
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Tumour-infiltrating Gr-1+ myeloid cells antagonize senescence in cancer - Nature (2014) vol. 515 pp134-7
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Targeting endothelial junctional adhesion molecule-A/ EPAC/ Rap-1 axis as a novel strategy to increase
stem cell engraftment in dystrophic muscles - EMBO Mol Med (2014) vol. 6 pp239-58
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A molecular thermometer for nanoparticles for optical hyperthermia - Nano Lett (2013) vol. 13 pp2004-10
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